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Quantitative PCR (qPCR) analysis of fractionated adipocytes in lean mice confirmed that NDI1 expression prevents the decline in Pparg , Ppargc1b and Bmper in mice lacking adipocyte Bmal1 (Extended Data Fig

From these studies, we observed that only approximately 50% of the semaglutide was retained in these hydrogels, while nearly 100% of the liraglutide was retained over prolonged timeframes in this release format where hydrogel erosion is negligible over time (Figure 3D

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